Cognition and Motivation

Picower Institute scientists study behaviors and cognitive processes including learning, memory, emotion, reasoning and consciousness. To learn more about these or other areas of inquiry, select them under Research Topics and you'll find relevant Picower people, discoveries and events.

Like radar, a brain wave sweeps a cortical region to read out information held in working memory

October 20, 2025
Research Findngs
When spotting what’s changed from one scene to the next, performance will depend on a low-frequency “theta” brain wave that scans the mental image, a new MIT study shows.

Many Mechanisms of Mood

September 29, 2025
Research Feature
Picower Institute studies reveal a number of ways moods emerge in the brain and therefore many potential paths to address depression, PTSD, anxiety and bipolar disorder.

How the brain splits up vision without you even noticing

September 22, 2025
Research Findngs
As an object moves across your field of view, the brain seamlessly hands off visual processing from one hemisphere to the other like cell phone towers or relay racers do, a new MIT study shows.

Aging Brain Initiative seed grants fund five new projects to address neurodegenerative disease

June 9, 2025
New Research
Campuswide collaboration sparks new research to develop assistive technology, enhance interventions, decipher brain biochemistry, advance big data analysis, and assess the public’s understanding of dementia risk and protective factors.

The how and why of the brain’s division across hemispheres

May 12, 2025
Research Findings
Why does the brain split visual spatial perception between its hemispheres? A new review examines the advantages and trade-offs, and how the brain ultimately makes vision feel seamless.

Different anesthetics, same result: unconsciousness by shifting brainwave phase

May 12, 2025
Research Findings
MIT study finds that an easily measurable brain wave shift may be a universal marker of unconsciousness under anesthesia

Dopamine signals when a fear can be forgotten

April 28, 2025
Research Findings
Study shows how a dopamine circuit between two brain regions enables mice to extinguish fear after a peril has passed.

In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity

April 24, 2025
Research Findngs
Study provides new evidence that sensory stimulation of gamma-frequency brain rhythm may promote broad-based restorative neurological health response.

With Searle Scholar award, Fan will study serotonin role in memory

April 22, 2025
Picower People
Assistant Professor Linlin Fan will apply her lab’s precise “all-optical” techniques to study how serotonin might influence plasticity in memory, and whether psychedelics affect that.

In kids, EEG monitoring of consciousness safely reduces anesthetic use

April 21, 2025
Research Findings
Clinical trial finds several outcomes improved for young children when an anesthesiologist observed their brain waves to guide dosing of sevoflurane during surgery.

A simple animal’s response to sickness highlights the nervous system’s surprising degrees of flexibility

April 8, 2025
Research Findings
Upon infection, the C. elegans worm reshuffles the roles of brain cells and flips the functions of some of the chemicals it uses to regulate behavior.

A neuron’s neighbors

March 14, 2025
Research Feature
The field is called neuroscience, but neurons alone can’t operate your brain. Research is revealing how non-neural cells indispensably contribute to function, and why their roles can make them promising treatment targets in disease.