Li-Huei Tsai … DSB accumulation is an early pathological hallmark of neurodegeneration. Based on snRNAseq on postmortem samples … from human AD patients and the CK-p25 mouse model of neurodegeneration, we found that DSB accumulation leads to …
Myriam Heiman … spiny neurons neuronal identity Huntington's Disease neurodegeneration Single Cell Transcriptomics and Epigenomics …
Laura Lewis … Disease Sleep fMRI EEG attention depression aging neurodegeneration thalamus 36-730 ldlewis@mit.edu Lewis Lab …