August 08, 2017
Blocking a key enzyme may reverse memory loss
… by blocking its interaction with a binding partner called Sp3. “This is exciting because for the first time we have … further testing. Those tests revealed that a gene called Sp3 is necessary to recruit HDAC2 to chromatin to enact its … a nearly perfect correlation between levels of HDAC2 and sp3. Specific targets The researchers then explored what …