… techniques aims to discover mechanisms underlying ALS and frontotemporal lobar degeneration with motor neuron … By uncovering the underlying molecular mechanisms of how cell viability fails amid TDP-43, they’ll gain insights into … we are seeing in the field is a general shift from the single-candidate, single hypothesis model to let’s truly …
… Neuroscientists at MIT have now shown that two distinct cell populations in the striatum are affected differently by … and one of the senior authors of the study . Using single-cell RNA sequencing to analyze the genes expressed in … probably involve the striatum, and now, partly through transcriptomics, we’re working to understand how all of this …
… with an unusually deep characterization of how the two cell types differ in form and function and then took a highly … molecular components. Research Article neuronal identity , SingleCellTranscriptomicsandEpigenomics , drosophila , synapse …
… of disease progression The complexity of understanding and treating Huntington’s disease, a fatal neurodegenerative … degrees of Huntingtin mutation in a wide variety of cell types – not only SPNs but also neurons that connect to … FTLD show strong molecular overlaps, new study shows Single-cell gene expression patterns in the brain’s motor and …
… FTLD show strong molecular overlaps, new study shows Single-cell gene expression patterns in the brain’s motor and … neurodegeneration , neurological disorders , SingleCellTranscriptomicsandEpigenomics , cerebrovasculature , motor …
… complexity of Alzheimer’s disease By analyzing epigenomic and gene expression changes that occur in Alzheimer’s … epigenomic, and transcriptomic changes that occur in every cell type in the brains of Alzheimer’s patients. Using more … focused on gene expression changes, the researchers used single-cell RNA-sequencing to analyze the gene expression …