… IGF1 RettSyndrome, a devastating neurological disorder that typically … (of which girls have two) account for the vast majority of RettSyndrome cases. Years of basic research on genes involved in …
… and applying them to study conditions such as Down syndrome, Alzheimer’s disease, Rettsyndrome, and Zika virus infection. While the whole … findings by using iPSCs as part of its studies of Rettsyndrome, an autism-like disorder. In a study published …
… , is likely consequential in people with 16p11.2 deletion syndrome . Accounting for up to 1 percent of autism cases, … protein-encoding genes leads to clinical symptoms of the syndrome such as autism-like behaviors, developmental delay … be among the 29 affected in people with 16p11.2 deletion syndrome, its specific function in neurons has barely been …
… basic research origin of the first approved drug to treat Rettsyndrome March 10, 2023 3 questions for Mriganka Sur: The … basic research origin of the first approved drug to treat Rettsyndrome On March 10 the FDA approved Trofinetide, a …
… One cause of autism and intellectual disability, fragile X syndrome, is a direct result of a mutation that causes loss … deficits in fragile X mice. Above: A boy with fragile X syndrome. Picture by Peter Saxon/Wikimedia Commons CC BY-SA … conditions. In 2016 they reported that mice modeling Rettsyndrome benefitted from mGluR5 inhibitors and the …