… in the early ‘90s Tsai identified a particular enzyme, Cdk5, that turned out to only be active in the nervous system. Tsai’s studies of Cdk5 revealed that it was crucial for neural development, in … the migration of newly born neurons to the cortex. Without Cdk5, the brain wouldn’t form its characteristic lamination, …
… studies on a protein called cyclin-dependent kinase 5 or Cdk5, which has been found to affect neurodegenerative … disease. She has provided important evidence that Cdk5 is an important mediator of deficits found in …