Colloquium with Marcy MacDonald, PhD, Massachusetts General Hospital, Harvard Medical School … genetic cause of the disorder is an expanded, unstable CAG triplet repeat located in the HD gene (HTT), that encodes … focus has been on Huntington’s disease, with its unstable CAG triplet repeat expansion mutation in the HD gene on …
Genes & Disease December 14, 2020 … just one type of mutation—an accumulation of repeati ng CAG tri nucleo tides in the Huntingtin gene—causes toxic …
Cutting Edge Approaches to Studying the Aging Brain … Lab Multi-omics analyses reveal overlapping impact of CAG repeat expansion and HTT knockout on Huntington’s Disease …