Disorders | Picower Institute

Picower Institute scientists investigate the pathophysiological mechanisms underlying complex disorders of the brain that affect emotion and cognition. To learn more about research in these or other areas, select them under "Research Topics" and you'll find relevant Picower people, discoveries and events.

August 29, 2023

Research Findings

A potential new Alzheimer’s drug represses the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and improving cognition in preclinical tests

June 22, 2023

Research Feature

Why studying simple organisms—none larger than the palm of your hand—is so integral to understanding nervous system health, disease and evolution.

June 13, 2023

Picower People

‘Career Award at the Scientific Interface’ recognizes Rebecca Pinals’ research to create a nanosensor-integrated brain-on-a-chip model of Alzheimer’s disease.

June 1, 2023

Research Findings

MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.

May 18, 2023

Picower Events

Symposium speakers describe numerous ways to promote prevention, resilience, healing and wellness after early life stresses

May 18, 2023

Research Findings

Tactile stimulation improved motor performance, reduced phosphorylated tau, preserved neurons and synapses and reduced DNA damage, a new study shows

April 19, 2023

Research Findings

Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.

April 12, 2023

Research Findings

The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.

April 10, 2023

Research Findings

Blood flow induced by visual stimulation drives the flow of cerebrospinal fluid

March 1, 2023

Research Feature

Neuroscientists are finding that immune system activity within the brain and the body has important impacts on mental health and behavior

February 2, 2023

Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue

January 20, 2023

Research Findings

A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement